1.  You are working in a lab and need to anesthetize a small rat.  You plan to put the rat in a closed plastic container and inject an amount of liquid sevoflurane to produce an induction concentration of 4%.  If the container has a volume of 2 liters, how much sevoflurane should you inject?

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2.  You get to the lab and find out that the sevoflurane bottle is empty, but there is a full bottle of isoflurane.  You use it instead of sevoflurane.  How much isoflurane do you inject?

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3.  As you are about to start your experiment, you drop the 100 ml isoflurane bottle on the floor and it smashes liberating all of the isoflurane.  The lab is a square room, 20 feet by 20 feet with a ceiling of height of ten feet.  This is a weird lab and it has no ventilation.  Is everyone in the lab going to fall asleep?  Explain your answer.

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4.  So, now that you know what you know from questions 1-3, how much liquid sevoflurane should I inject into the expiratory limb of a closed 10 liter anesthetic circuit to produce a 2% concentration?

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